Preventing Arthritis with Complete Animal Joint Care
What is Arthritis and How Does it Affect Animal Joint Care? Arthritis is an inflammatory response to joint trauma or disease that causes further damage to joints when the inflammation becomes chronic.
- One out of three cats will develop arthritis during their lifetime.
- One out of every five dogs less than seven years of age are affected by joint injury or disease
- Finally, seven out of ten senior dogs over 7 years of age suffer from arthritis
All total, it is estimated that over 14 million pets in the U.S. have arthritis – some as young as one year of age. Unfortunately, only a small percentage of these animals are receiving treatment.
The joints of your pet’s body are composed of soft connective tissue and cartilage. Their role is to provide cushioning between bones and to allow normal movement. The active lifestyle of our pets makes their joints susceptible to injury, which is why animal joint care is important.
The Causes of Arthritis:
- Developmental disorders, such as hip or elbow dysplasia
- High calorie, carbohydrate-based diets that provide excessive energy during growth causing the body to grow faster than the cartilage producing deficits
- Injury or trauma to a joint such as a ruptured anterior cruciate ligament (ACL)
- Bacterial or tick-borne infections
- Autoimmune disorders that cause your pet’s immune system to attack itself
Osteoarthritis is the most common form of joint disease in pets. It is characterized by the breakdown of cartilage in one or more joints accompanied by inflammation and pain that progresses to a debilitating condition that can severely affect joint mobility and health.
Early Injuries Can Lead to Arthritis in a Pet’s Later Years. Many joint diseases in middle-aged or older pets develop as a result of an earlier (sometimes much earlier), often seemingly minor injury or trauma.
Common symptoms of Osteoarthritis
- Erosion of Cartilage
- Loss of Joint Lubrication
- Loss of Mobility and Flexibility
- Atrophy of Surrounding Muscles
Identifying Joint Disease
Your dog can’t explain what’s wrong with him, so it’s important to watch his non-verbal cues closely and take even subtle changes seriously.
Signs that your dog may have joint problems:
- Favoring a limb
- Difficulty sitting or standing
- Weight gain
- Hesitancy to run, jump or climb stairs
- Decreased activity or interest in play
- Becoming less alert and responsive
- Attitude or behavior changes
It can be much harder to spot arthritis in a cat. Cats are stoic when they don’t feel well and they rarely limp even in the presence of a painful condition like arthritis.
In cats, look for any behavior changes that signal an underlying problem such as:
- Reluctance to jump
- Eliminating outside the litter box
- Decreased interest in family members and other pets
- No longer covering his urine or feces with litter
- Lack of appetite
- Becoming less active
- Sleeping more
- Muscle wasting in the legs
If a dog or cat appears to have any of these symptoms for more than two weeks – take him to your veterinarian for an evaluation. This may include a physical exam, X-rays or even more advanced diagnostic procedures. The best thing you can do in the overall management of a joint problem is to get a proper diagnosis and start a treatment plan as soon as possible.
The Osteoarthritis Process
Initiation (how osteoarthritis begins)
- Aging, stress or injury produces wear and tear on the joint cartilage
- Body reacts by secreting pro-inflammatory cytokines and adhesion molecules
- Inflammation builds until the threshold is met
- When the inflammation threshold is reached
- The immune system sends Killer T-cells to the inflammatory site
- Killer T-cells activate the production of collagen-specific antibodies from B-cells
- The antibodies migrate and bind to the joint cartilage
- Antibody-tagged cartilage is then targeted by macrophages
- Macrophages release a powerful enzyme that breaks down collagen
- Erosion of the cartilage surface follows
Continued exercise or movement within the damaged joint causes a cyclic acceleration of the inflammatory phase resulting in:
- Increased pain
- Loss of mobility and flexibility
- Further erosion of joint cartilage
- Resulting Atrophy of surrounding muscles
- Weakening of supporting ligaments and tendons
The Complete Animal Joint Care Solution
Complete Joint Care is the most comprehensive, natural Joint Formula available today. Complete Joint Care contains the proprietary Aliva® Joint Support Complex; key ingredients that work synergistically to control the events that allow joint damage to become a chronic destructive and debilitating disease.
Breaking the Osteoarthritis Cycle
Green Lipped Mussel Extract (GLME™) is a powerful and completely natural Cox-2 inhibitor that can block the cyclooxygenase pathway limiting the secretion of pro-inflammatory cytokines and adhesion molecules thus blocking the inflammatory threshold from being met.
GLME and Type II Collagen have both demonstrated their ability to suppress the activation of Killer T-cells thereby greatly reducing the number of B-cell collagen specific antibodies that can attach to the cartilage surface
With the amount of antibody tagged collagen greatly reduced the body stops sending macrophages to the area and the destructive phase is greatly diminished.
Without the inflammatory cycle repeating itself, the joint can actually begin healing itself. For healing to occur the joint needs collagen producing precursors (Chondroitin) that is uniquely supplied in its natural form by both the GLME and Type II collagen. In addition, GLME and Type II collagen are rich in Hyaluronic acid which helps bring back natural lubrication of the joint surface.
When a limb is not used for a period of time due to pain and inflammation the surrounding muscles, ligaments and tendons begin to atrophy (lose their size and strength). This leads to destabilization of the joint and additional damage to the collagen surface. In order to strengthen the atrophied muscles and supporting structures the Aliva® Joint Support Complex includes β-hydroxy-β-methylbutyrate (HMB). HMB, a Leucine metabolite, has been proven in scientific studies to increase muscle size and strength by over 20% even when exercise is being restricted. In addition, Complete Joint Care provides TendoGuardTM to strengthen the ligaments and tendons that provide stability to the joints of the body.
Aliva® Joint Support Complex
1. GlycoMarine™ New Zealand Green Lipped Mussel Extract (GLME)
GlycoMarine™ is a freeze dried powder prepared by patented process from a liquid extract of the Green Lipped Mussel Perna canaliculus. Unlike the commonly used Green Lipped Mussel Powders, GlycoMarine™ is a proven Cox-2 inhibitor similar in strength to most NSAID drugs.
GlycoMarine™ is currently used for the treatment of both rheumatoid and osteoarthritis in both human and animal subjects. It is classified as a chondroprotective nutraceutical and has the backing of 30 years of peer-reviewed research to support its pharmacological activity. The main reason for its extensive use is that it is an effective, natural anti-inflammatory with selective cyclooxygenase (COX-2) inhibitory properties that can be used on a long term basis without the complication of any adverse side effects.
- Anti-inflammatory – GlycoMarine™ inhibits both the cyclooxygenase and 5-lipoxygenase enzyme cascades with COX-2 selectivity. These functions are a response to the lipid component of the extract.
- GlycoMarine™ also inhibits a number of pro-inflammatory neutrophil functions including: neutrophil emigration, catabolic cytokines and the mediation of T-lymphocyte activity. These functions are a response to the carbohydrate component of the extract.
- Chondroprotection – GlycoMarine™ inhibits the catabolic degradation of articular cartilage and enhances the lubrication and buffering of arthritic joints. GlycoMarine™ provides natural Chondroitin and Hyaluronic Acid to support rapid healing and the return to optimum joint health. This activity is a response to the amino acid and glycosaminoglycan content of the extract.
- Gastroprotection – GlycoMarine™ protects the stomach unlike the ulcerogenic effects of non-steroidal anti-inflammatory drugs. This activity is a response to the lipid component of the extract.
- Pain relief – GlycoMarine™ relieves pain as a result of its natural anti-inflammatory and chondroprotective properties.
Note: By directly supplying Chondroitin and Hyaluronic Acid – GlycoMarine™ far surpasses Glucosamine when it comes to providing joint matrix components.
2. Type II Collagen
Type II Collagen is the major component of articular joint cartilage. Our Aliva® Joint Support Complex uses a unique, patented Type II Collagen derived exclusively from avian (Chicken) sternum cartilage. The specific manufacturing process optimizes the low molecular weight for maximum absorption without affecting its beneficial effects on joint health. Aliva® Joint Support Complex Type II collagen has a protein content of 65-70% with 18 specific long chain amino acids that remain intact ensuring the animals natural enzymes will recognize the precise genetic code for maximum assimilation and ultimate joint health results.
This Type II Collagen additionally supplies 25 – 30% naturally occurring mucopolysaccharides consisting of natural Chondroitin and Hyaluronic acid that are essential for the production of collagen cells and the biosynthesis of synovial fluid.
Research has demonstrated that our Aliva® Joint Health collagen works with the immune system to deactivate collagen-specific T cells which prevents the secretion of enzymes responsible for the breakdown of joint collagen. Once the immune system is alerted to stop attacking its own collagen, the numbers of inflammatory cytokines that trigger the damaging inflammatory reaction are decreased resulting in a slowing and then stopping of the destructive cycle of collagen erosion in the joints. This allows the body the opportunity to ultimately rebuild cartilage and heal affected joints.
3. HMB (β-hydroxy-β-methylbutyrate)
HMB is a unique nutritional ingredient produced naturally in the body from the essential amino acid Leucine. As one of the essential amino acids, the dog is unable to synthesize it. Therefore, it must be obtained either through diet or supplementation.
HMB is a fifth generation metabolite of Leucine, which functions at a much higher level in the body as a primary component or building block of muscle tissue. In situations where metabolic demand is high as in rigorous exercise, disease processes or rehabilitation – the body cannot supply sufficient amounts of HMB to meet specific tissue needs. In these situations, dietary supplementation of HMB has been shown to be highly advantageous in maintaining maximum muscle size and strength, preventing muscle wasting and reversing muscle atrophy.
Both human and animal studies have shown that HMB is a critical element in preserving muscle size and function and is capable of slowing the loss of muscle associated with stress and disease. It has also been proven capable of increasing muscle strength and functional ability by up to 33% in adult and senior animals.
HMB strengthens the muscles that support joint stability helping animals return to a more active, flexible and mobile state. As such, it is considered to be a vital component in osteoarthritic conditions. HMB has also been shown in numerous human and animal studies to be completely safe. Ross Labs uses HMB in their human post-operative hip replacement protocols to improve recovery time and has recently added HMB to its popular senior drink Ensure.
100% Avian Eggshell Membrane & Chicken Sternum Cartilage
U.S Patent #8,344,106 B1
TendoGuard™ is a proprietary (patented) dietary supplement formula containing a perfect balance of collagen Type I, Type II, Type V, Type X, Hyaluronic Acid, Chondroitin Sulfate and Mucopolysaccharides.
TendoGuard™ naturally contains anti-inflammatory and antibacterial compounds to support tendon recovery and to maintain healthy and strong mechanical properties of tendon, bone, and joint functions.
Additional Animal Joint Care
Oxidative cellular destruction is greatly accelerated during most disease processes especially chronic inflammatory diseases like arthritis. To protect against increased cellular damage, Complete Joint Care includes a powerful blend of known antioxidants responsible for removing free radicals that cause cellular damage in the dog and cat.
Supporting Joint Health
- Weight Control – maintaining normal body weight in dogs is the most proactive thing you can do to help prevent or manage osteoarthritis. Weight loss is a matter of balancing the number of calories going in with the amount being expended. Safe and effective weight loss can be accomplished by reducing a dog’s regular diet by 25% and replacing the lost nutrients with Canine or Feline Fitness & Health products. It is the most complete and balanced nutritional supplement available.
- Exercise – is one of the most important aspects of keeping a dog fit and healthy. When faced with joint disease, exercise should be limited to leash walking, swimming or other low-impact exercises until the joint becomes stabilized and muscle atrophy is reversed. Just controlling pain and allowing a dog to over-exercise will thwart any attempt by the animal to reconstruct damaged cartilage and will cause the osteoarthritis cycle to continue.
- Steroid and NSAID Treatment – may be effective in relieving pain and discomfort when an animal first presents with osteoarthritis but, is not a safe long-term strategy. Starting an animal on ArthraPro™ at the same time will greatly limit the need for additional steroid or NSAID therapy thereby minimizing the potential side effects usually associated with these medications.
- Prevention – Proactive supplementation of specific joint health ingredients in large breed dogs, athletic animals and those breeds having a high incidence of hip dysplasia is also highly recommended. Choosing a safe and effective product early in life may go a long way towards eliminating more costly and painful events down the road.
- If you use a choke collar or common neck style leash, cervical damage can result from dogs that pull, leap or jerk against the collar or owners that believe jerking back on the collar is a good way to correct poor behaviors while walking.
Check out our products for Arthritis and Joint Support.